Background:

The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.

Applications:

ELISA, WB, IHC

Name of antibody:

XPNPEP3

Immunogen:

Fusion protein of human XPNPEP3

Full name:

X-prolyl aminopeptidase 3

Synonyms:

APP3; ICP55; NPHPL1

SwissProt:

Q9NQH7

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and Human tonsil

IHC Recommend dilution:

30-150

WB Predicted band size:

57 kDa

WB Positive control:

PC-3 and 293T cell lysates

WB Recommended dilution:

200-1000